4Q Spread: Cardinals (-4.5)

Prediction market on polymarket. In the fourth quarter of the NFL game between Cardinals and 49ers, scheduled for September 27 at 4:05 PM ET: This market will resolve to "Cardinals" if the Cardinals outscore the 49ers by 5 or more points in the fourth quarter. Otherwise, this market will resolve to "49ers". Only points scored during that period count; overtime is not included. If the game is postponed, this market will remain open until the game has been completed. If the game is canceled entirely, with no make-up game, this market will resolve 50-50.

Resolves: 9/27/2026.