Will humanity survive until 2100?

Prediction market on manifold. Full question: Humanity will not go extinct before 2100. At least 1 thousand humans or human descendants (e.g., mind uploads) will be alive in 2100. One of the questions from https://jacyanthis.com/big-questions. Resolves according to my judgement of whether the criteria have been met, taking into account clarifications from @JacyAnthis, who made those predictions. (The goal is that they'd feel comfortable betting to their credance in this market, so I want the resolution criteria to match their intention.)

Liquidity: $1,135. Resolves: 1/1/2100.